Distek Opt-Diss 410

In-Situ Fiber Optic UV System for Dissolution Testing

The Opt-Diss 410 brings dissolution measurement directly to the vessel, eliminating the need for manual or automated sampling along with the associated consumables, labour, and off-line analysis. Choose from our patented ARCH probes, designed specifically for dissolution testing, or the new patent pending Variprobe Adjustable Pathlength Dip Probe. Moving light into the vessel rather than pumping the liquid out allows for near real-time data acquisitions and nearly limitless sample points. All while requiring no complicated manifolds, media return, or tedious volume correction calculations.
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RAPID DATA COLLECTION
Acquisition speeds as fast as 5 seconds for all vessels.
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ROUTINE COLLECTION OF COMPLETE PROFILES
Collecting near real-time dissolution profiles is ideal for formulators to understand complicated release dynamics as it occurs.
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MULTICOMPONENT ANALYSIS SOFTWARE
The use of state of the art software makes it possible to easily quantify two components at once, without the need for chromatographic separation. This means the speed and ease UV measurement can now be applied to an even broader class of products with two APIs or interfering component like excipients, coatings, capsules, etc., without the need for time consuming HPLC analysis.​
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STATIONARY ARCH PROBES
Designed specifically for dissolution testing, the patented probes virtually eliminate the entrapment of bubbles and particles that plague other fibre systems. The ARCH probes small hydrodynamic cross section also alleviates the need for a complicated raising and lowering sampling manifold.
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SINGLE DETECTOR WITH NO MOVING PARTS
The Opt-Diss 410 uses a scientific 2-D CCD multichannel detector and spectrograph that allow for the acquisition of the entire spectral range (200 to 400 nm) from all vessels simultaneously with one detector. This eliminates the inter-channel variability encountered with multi-detector systems or other single detector systems that require a multiplexer.