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ASMS 2026 brought a wave of new mass spectrometry instruments, software and accessories, with suppliers focusing on greater sensitivity, faster workflows and easier data analysis.
The 2026 American Society for Mass Spectrometry event, held in San Diego from 31 May to 4 June 2026, introduced a wide range of new instruments, software tools and accessories designed to improve lab performance. The biggest themes were clear: higher sensitivity, faster analysis, simpler workflows and better software support. [*]
Mass spectrometers were the main focus. Suppliers showed new systems that can detect lower-abundance molecules, process more complex samples and deliver results more quickly. Across the board, manufacturers emphasised the same goal: making advanced mass spectrometry more practical and scalable for real-world lab use. [*]
Waters introduced several new platforms. The Xevo CDMS measures both mass and mass-to-charge ratio for individual particles, making it possible to study extremely large biomolecules. The company also launched the Cyclic IMS P20, which combines ion mobility with high-resolution time-of-flight analysis to improve sensitivity and speed. Another addition, the Xevo MRT P10, is aimed at high-throughput multiomics work and offers stronger performance for fast, data-rich workflows. [*]
Bruker presented the timsMRMS, which combines high-resolution mass detection with gas-phase separation. The company positioned it as a high-end solution for generating extremely detailed data from complex mixtures, with potential applications ranging from proteomics to fuel and battery research. [*]
Agilent launched the 9500 ICP-QQQ, a new ICP/MS platform designed to improve both performance and ease of use. The company highlighted faster acquisition times, simpler operation and better energy efficiency. Sciex introduced the Novus V55, its fifth-generation triple quadrupole system, built to support faster testing across areas such as food analysis, pharmaceutical impurities and PFAS testing. [*]
Thermo Fisher Scientific also revealed several major additions. The Orbitrap Tribrid Apex combines three mass analysers on one platform and is designed to improve speed, sensitivity and mass range. The Orbitrap Excedion is aimed at pharmaceutical and biopharmaceutical labs, with a focus on more complete and regulatory-ready data. The Orbitrap Exploris GC S is built for very low-level contaminant detection in environmental and food safety testing. [*]
Software was another major area of innovation. The article highlights how AI and machine learning are playing a growing role in both data analysis and instrument performance. New tools included Science Machine, a browser-based platform that automates data processing from raw files to final reports; Shimadzu LabSolutions Insight Profiler, designed to simplify non-targeted LC/MS analysis; and Sciex OS 5.0, which adds instrument monitoring, reporting tools and AI-driven support features. [*]
Chromatography products also featured strongly. Agilent introduced the 8890B GC, an updated gas chromatograph with improvements such as faster cooling, better monitoring and sustainability credentials. Phenomenex launched new Endrix and Luna Omega HILIC columns, while Shimadzu unveiled the Nexera X4 UHPLC, designed to support faster analysis and stronger LC/MS performance. [*]
There were also supporting technologies aimed at improving lab workflows. Shimadzu highlighted SICRIT, a versatile ion source developed through its acquisition of a majority stake in Plasmion. Peak introduced the Genius Neo nitrogen generator, which offers high purity output with lower power use. Evosep launched the Lupo, an automation system designed to reduce variability in sample preparation and support more scalable proteomics. [*]
Taken together, the product launches at ASMS 2026 show where the sector is moving: towards systems that generate better data, process samples faster and reduce friction for users. For laboratories working in research, pharma, environmental testing and applied science, these developments could support earlier disease detection, stronger workflows and more confident decision-making.
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